When I picked up my car from the dealer, the TMPS readings were all showing 40. I let the car sit overnight, and checked the pressures with three different gauges - two stick type, and a known accurate accutire digital gauge. I adjusted the fronts to 33, and the rears at 32 per the door plate. The TPMS display shows 30 and 29 respectively, so it's pretty much on a -3 and it is consistent. Not sure if it's a problem I should be concerned about or not.
My dealer puts nitrogen in the tires (high altitude, and large temp swings depending on season), but pressure is pressure. I wouldn't think that would affect the sensors at all, but I am sure someone knows more than I do on that subject.